Reaction Details Report a problem with these data
Target
Transcriptional activator protein LasR
Ligand
BDBM50527020
Substrate
n/a
Meas. Tech.
ChEMBL_1901836 (CHEMBL4404058)
IC50
15000±n/a nM
Citation
 Chbib, C Impact of the structure-activity relationship of AHL analogues on quorum sensing in Gram-negative bacteria. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LasR
Synonyms:
LASR_PSEAE | lasR
Type:
PROTEIN
Mol. Mass.:
26618.24
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_1475312
Residue:
239
Sequence:
MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL
  
Inhibitor
Name:
BDBM50527020
Synonyms:
CHEMBL4538227
Type:
Small organic molecule
Emp. Form.:
C19H29NO2
Mol. Mass.:
303.4391
SMILES:
CCCCCCCCCNC(=O)CC(=O)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: