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Target
Proteasome subunit beta type-5
Ligand
BDBM50380997
Substrate
n/a
Meas. Tech.
ChEMBL_1930128 (CHEMBL4433379)
IC50
178±n/a nM
Citation
 Golonko, A; Pienkowski, T; Swislocka, R; Lazny, R; Roszko, M; Lewandowski, W Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system. Eur J Med Chem 167:291-311 (2019) [PubMed]  Article 
Target
Name:
Proteasome subunit beta type-5
Synonyms:
3.4.25.1 | Macropain epsilon chain | Multicatalytic endopeptidase complex epsilon chain | PSB5_RAT | Proteasome chain 6 | Proteasome epsilon chain | Proteasome subunit X | Proteasome subunit beta type-5 | Psmb5
Type:
PROTEIN
Mol. Mass.:
28586.62
Organism:
Rattus norvegicus
Description:
ChEMBL_118958
Residue:
263
Sequence:
MALASVLQRPMPVNQHGFFGLGGRADLLDLGPGSPGDGLSLAAPSWGVPEEPRIEMLHGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHDKYTSSIP
  
Inhibitor
Name:
BDBM50380997
Synonyms:
BROUSSONIN B
Type:
Small organic molecule
Emp. Form.:
C16H18O3
Mol. Mass.:
258.3123
SMILES:
COc1cc(O)ccc1CCCc1ccc(O)cc1
Structure:
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