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Target
S-formylglutathione hydrolase
Ligand
BDBM50543567
Substrate
n/a
Meas. Tech.
ChEMBL_1989375 (CHEMBL4623110)
Kd
0.800000±n/a nM
Citation
 Chen, X; Yang, Y; Su, L; Cui, X; Shao, J; Liu, S; Zhao, B; Miao, J Finding the mechanism of esterase D activation by a small molecule. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
S-formylglutathione hydrolase
Synonyms:
3.1.1.56 | 3.1.2.12 | ESD | ESTD_HUMAN | Esterase D | FGH | Methylumbelliferyl-acetate deacetylase | S-formylglutathione hydrolase
Type:
PROTEIN
Mol. Mass.:
31465.46
Organism:
Homo sapiens
Description:
ChEMBL_105460
Residue:
282
Sequence:
MALKQISSNKCFGGLQKVFEHDSVELNCKMKFAVYLPPKAETGKCPALYWLSGLTCTEQNFISKSGYHQSASEHGLVVIAPDTSPRGCNIKGEDESWDFGTGAGFYVDATEDPWKTNYRMYSYVTEELPQLINANFPVDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVLCPWGKKAFSGYLGTDQSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFIAACTEKKIPVVFRLQEGYDHSYYFIATFITDHIRHHAKYLNA
  
Inhibitor
Name:
BDBM50543567
Synonyms:
CHEMBL4635246
Type:
Small organic molecule
Emp. Form.:
C20H16ClN3O
Mol. Mass.:
349.814
SMILES:
Oc1ccc(Cl)cc1C1=NN(C(C1)c1ccccc1)c1ccccn1 |t:9|
Structure:
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