Reaction Details Report a problem with these data
Target
Growth hormone secretagogue receptor type 1
Ligand
BDBM50552133
Substrate
n/a
Meas. Tech.
ChEMBL_2033594 (CHEMBL4687752)
EC50
1.3±n/a nM
Citation
 Talele, TT Opportunities for Tapping into Three-Dimensional Chemical Space through a Quaternary Carbon. J Med Chem 63:13291-13315 (2020) [PubMed]  Article 
Target
Name:
Growth hormone secretagogue receptor type 1
Synonyms:
GH-releasing peptide receptor | GHRP | GHS-R | GHSR_RAT | Ghrelin receptor | Ghsr | Growth hormone secretagogue receptor type 1
Type:
PROTEIN
Mol. Mass.:
40970.19
Organism:
Rattus norvegicus
Description:
ChEMBL_11556
Residue:
364
Sequence:
MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
  
Inhibitor
Name:
BDBM50552133
Synonyms:
CHEMBL4765101
Type:
Small organic molecule
Emp. Form.:
C28H38N4O5S
Mol. Mass.:
542.69
SMILES:
CC(C)(N)NC(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC2(CC(c3ccccc23)S(C)(=O)=O)CC1 |r|
Structure:
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