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TargetG-protein coupled receptor 183
LigandBDBM50558428
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2063684
EC50 1.1±n/a nM
Citation Deng, XSun, SWu, JKuei, CJoseph, VLiu, CMani, NS Fluoro analogs of bioactive oxy-sterols: Synthesis of an EBI2 agonist with enhanced metabolic stability. Bioorg Med Chem Lett26:4888-4891 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
G-protein coupled receptor 183
Name:G-protein coupled receptor 183
Synonyms:EBI2 | EBV-induced G-protein coupled receptor 2 | Epstein-Barr virus-induced G-protein coupled receptor 2 | G-protein coupled receptor 183 | Gpr183
Type:PROTEIN
Mol. Mass.:40250.74
Organism:Rattus norvegicus
Description:ChEMBL_120274
Residue:357
Sequence:
MANNFTTPLAASHGNNCDLYAHHSTARILMPLHYSLVFIIGLVGNLLALVVIVQNRKKIN
STTLYSMNLVISDILFTTALPTRIVYYALGFDWRIGDALCRITALLFYINTYAGVNFMTC
LSIDRFFAVVHPLRYNKIKRIEYAKGICVFVWILVFAQTLPLLLKPMSKQEADKTTCMEY
PNFEGTASLPWILLGACLLGYVLPLAIILLCYSQICCKLFRTAKQNPLTEKSGVNKKALN
TIILIIGVFVLCFTPYHVAIMQHMVKTLYAPGALGCGVRHSFQISLHFTVCLMNFNCCMD
PFIYFFACKGYKRKVMKMLKRQVSVSISSAVRSAPEENSREMTESQMMIHSKASNGR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50558428
NameBDBM50558428
Synonyms:CHEMBL4779254
TypeSmall organic molecule
Emp. Form.C28H45F3O3
Mol. Mass.486.6503
SMILES[H][C@@]1(CC[C@@]2([H])[C@@]3([H])[C@]([H])(CC[C@]12C)[C@@]1(C)CC[C@H](O)CC1=C[C@]3(O)C(F)(F)F)[C@H](C)CCCC(C)(C)O |r,c:24|
Structure
n/a