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Target
Beta-galactosidase
Ligand
BDBM50163440
Substrate
n/a
Meas. Tech.
ChEMBL_344326 (CHEMBL869584)
Ki
12500±n/a nM
Citation
 Greimel, P; Häusler, H; Lundt, I; Rupitz, K; Stütz, AE; Tarling, CA; Withers, SG; Wrodnigg, TM Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols. Bioorg Med Chem Lett 16:2067-70 (2006) [PubMed]  Article 
Target
Name:
Beta-galactosidase
Synonyms:
BGAL_RHIML | lacZ
Type:
PROTEIN
Mol. Mass.:
84164.14
Organism:
Rhizobium meliloti
Description:
ChEMBL_344326
Residue:
755
Sequence:
MRSVTSFNDSWVFSEASTRDAERSGRVSRSACRTNAVELPFNYFDERCYQRAFTYQRVLAWRPDFSQGSRSSSTRQWPMRSCISTAKRSSRIRDGYTPFEARLTDRLLEGDNLITVKIDGSENPEIPPFGAGIDYLTYAGIYRDVWLKVTDPVSIANIKIETRDVLSDHKAVSLRCDLSNPQGLSFSGTISALLKNAAGEVLAEVAGETTGQSLAFEMDGLRGLSLWDIDDPVLYVIEVELRTGQGFRLLRRAFRLPHGEFTTEGFRLNGRPLKIRGLNRHQSFPYVGLRMGRTAKGSAHADIMNAHRLHCNLVRTSHYPQSKWFLDHCDRIGLLVFARNPRLAAYRWGGMETGGNPERPPHRSSATGTTRLSYIWGVRINESQDSHDFYAETNRLARELDPTRQTGGVRYITDSEFLEDVYTMNDFILGNEELPGANRPGTALRPQQECTGLPRKVPYLITEFGGHMYPTKIYDQEQRQAEHVRRHLEVLNAAYARNPGISGAIGWCMFDYNTTRISAPATGSAITASWTCSASPKFAAYVYASQCDPSEEIVMKPVTFWARGDDDIGGVLPLIVLTNCDEIELKYGSLTKRVGPDRENFPHLPHPPVVIDHRHFTKDELGVWGMKWESAEFTGFIAGKPVADLRMAADPVPTTLQVEADSKTLRREGRDTVRLILRALDQAGNVLPFLNDAVDIEIHGPARLVGPARIVLQGGSGFLAGVHGRRRHASSRSRRRGSAAAKLDLVALADGAASA
  
Inhibitor
Name:
BDBM50163440
Synonyms:
(2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | (2R,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol | 1-deoxygalactonojirimycin | CHEMBL110458 | D-galacto-1-Deoxynojirimycin | DGJ
Type:
Small organic molecule
Emp. Form.:
C6H13NO4
Mol. Mass.:
163.1717
SMILES:
OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: