Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50185262
Substrate
n/a
Meas. Tech.
ChEMBL_564596 (CHEMBL964036)
IC50
16400±n/a nM
Citation
 Lassiani, L; Pavan, MV; Berti, F; Kokotos, G; Markidis, T; Mennuni, L; Makovec, F; Varnavas, A Anthranilic acid based CCK1 receptor antagonists: blocking the receptor with the same 'words' of the endogenous ligand. Bioorg Med Chem 17:2336-50 (2009) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50185262
Synonyms:
(+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-phenylpropanoic acid | 2(R,S)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-3-phenylpropionic acid | 2-(2-(1H-indole-2-carboxamido)benzamido)-3-phenylpropanoic acid | CHEMBL202861
Type:
Small organic molecule
Emp. Form.:
C25H21N3O4
Mol. Mass.:
427.4519
SMILES:
OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
Structure:
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