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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50280296
Substrate
n/a
Meas. Tech.
ChEBML_1066
Ki
44±n/a nM
Citation
 Romero, AG; Darlington, WH; Piercey, MF; Lahti, RA Synthesis of metabolically stable arylpiperazine 5-HT1A receptor agonists Bioorg Med Chem Lett 2:1703-1706 (1992)    Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_MOUSE | Gpcr18 | Htr1a | Serotonin 1a (5-HT1a) receptor
Type:
Enzyme
Mol. Mass.:
46192.09
Organism:
Mus musculus (Mouse)
Description:
Q64264
Residue:
421
Sequence:
MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR
  
Inhibitor
Name:
BDBM50280296
Synonyms:
1,1-Dioxo-2-[(1R,2S)-2-(4-pyrimidin-2-yl-piperazin-1-ylmethyl)-cyclopropylmethyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one | CHEMBL48100
Type:
Small organic molecule
Emp. Form.:
C20H23N5O3S
Mol. Mass.:
413.493
SMILES:
O=C1N(C[C@@H]2C[C@@H]2CN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12
Structure:
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