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Target
Delta-type opioid receptor
Ligand
BDBM50450288
Substrate
n/a
Meas. Tech.
ChEBML_146639
EC50
1200±n/a nM
Citation
 Sagara, T; Okamura, M; Shimohigashi, Y; Ohno, M; Kanematsu, K Specific affinity labeling of μ opioid receptors in rat brain by S-activated sulfhydryldihydromorphine analogs Bioorg Med Chem Lett 5:1609-1614 (1995)    Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50450288
Synonyms:
CHEMBL2112189
Type:
Small organic molecule
Emp. Form.:
C22H23N3O5S2
Mol. Mass.:
473.565
SMILES:
[H][C@]12Oc3c4c(C[C@]5([H])C([C@H](C[C@@H]1O)SSc1ccc(cn1)[N+]([O-])=O)[C@]24CCN5C)ccc3O |TLB:29:28:9:4.5.6|
Structure:
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