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Target
Prostate-specific antigen
Ligand
BDBM50298752
Substrate
n/a
Meas. Tech.
ChEMBL_588029 (CHEMBL1048364)
Ki
27.5±n/a nM
Citation
 LeBeau, AM; Banerjee, SR; Pomper, MG; Mease, RC; Denmeade, SR Optimization of peptide-based inhibitors of prostate-specific antigen (PSA) as targeted imaging agents for prostate cancer. Bioorg Med Chem 17:4888-93 (2009) [PubMed]  Article 
Target
Name:
Prostate-specific antigen
Synonyms:
APS | Gamma-seminoprotein | KLK3 | KLK3_HUMAN | Kallikrein-3 | P-30 antigen | PSA | Prostate specific antigen | Prostate-specific antigen | Semenogelase | Seminin
Type:
PROTEIN
Mol. Mass.:
28747.53
Organism:
Homo sapiens (Human)
Description:
ChEMBL_959198
Residue:
261
Sequence:
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANP
  
Inhibitor
Name:
BDBM50298752
Synonyms:
(5S,8S,11S,14R)-11-(3-amino-3-oxopropyl)-5,8-bis(hydroxymethyl)-16-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazaheptadecan-14-ylboronic acid | CHEMBL573646
Type:
Small organic molecule
Emp. Form.:
C24H38BN5O10
Mol. Mass.:
567.397
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)OCc1ccccc1)B(O)O |r|
Structure:
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