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Target
Fatty acid-binding protein, liver
Ligand
BDBM50310988
Substrate
n/a
Meas. Tech.
ChEMBL_619185 (CHEMBL1102423)
Ki
8170±n/a nM
Citation
 Hertzel, AV; Hellberg, K; Reynolds, JM; Kruse, AC; Juhlmann, BE; Smith, AJ; Sanders, MA; Ohlendorf, DH; Suttles, J; Bernlohr, DA Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins. J Med Chem 52:6024-31 (2009) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, liver
Synonyms:
FABP1 | FABPL | FABPL_HUMAN | Fatty acid-binding protein, liver | Liver fatty acid binding protein (human L-FABP T94T)
Type:
Protein
Mol. Mass.:
14208.72
Organism:
Homo sapiens (Human)
Description:
human L-FABP
Residue:
127
Sequence:
MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI
  
Inhibitor
Name:
BDBM50310988
Synonyms:
4-{[2-(methoxycarbonyl)-5-(2-thienyl)-3-thienyl]amino}-4-oxo-2-butenoic acid | 4-{[2-methoxycarbonyl)-5-(2-thienyl)-3-thienyl]amino}-4-oxo-2-butenoic acid | CHEMBL1077990
Type:
Small organic molecule
Emp. Form.:
C14H11NO5S2
Mol. Mass.:
337.371
SMILES:
COC(=O)c1sc(cc1NC(=O)\C=C\C(O)=O)-c1cccs1
Structure:
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