Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50312972
Substrate
n/a
Meas. Tech.
ChEMBL_616078 (CHEMBL1102041)
Ki
14±n/a nM
Citation
 Eastwood, P; Gonzalez, J; Paredes, S; Nueda, A; Domenech, T; Alberti, J; Vidal, B Discovery of N-(5,6-diarylpyridin-2-yl)amide derivatives as potent and selective A(2B) adenosine receptor antagonists. Bioorg Med Chem Lett 20:1697-700 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50312972
Synonyms:
CHEMBL1081041 | Cyclopropanecarboxylic acid [4,2'3',4'']terpyridin-6'-ylamide
Type:
Small organic molecule
Emp. Form.:
C19H16N4O
Mol. Mass.:
316.3565
SMILES:
O=C(Nc1ccc(-c2ccncc2)c(n1)-c1ccncc1)C1CC1
Structure:
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