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Target
Urotensin-2 receptor
Ligand
BDBM50302274
Substrate
n/a
Meas. Tech.
ChEMBL_636753 (CHEMBL1167042)
Ki
64±n/a nM
Citation
 Maryanoff, BE; Kinney, WA Urotensin-II receptor modulators as potential drugs. J Med Chem 53:2695-708 (2010) [PubMed]  Article 
Target
Name:
Urotensin-2 receptor
Synonyms:
G-protein coupled receptor 14 | GPR14 | UR-II-R | UR2R_HUMAN | UTS2R | Urotensin II receptor | Urotensin-II
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42159.71
Organism:
Homo sapiens (Human)
Description:
Urotensin-II UTS2R HUMAN::Q9UKP6
Residue:
389
Sequence:
MALTPESPSSFPGLAATGSSVPEPPGGPNATLNSSWASPTEPSSLEDLVATGTIGTLLSAMGVVGVVGNAYTLVVTCRSLRAVASMYVYVVNLALADLLYLLSIPFIVATYVTKEWHFGDVGCRVLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRKLLALGTWLLALLLTLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGLLIGLLYARLARAYRRSQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQLLAQYHQAPLAPRTARIVNYLTTCLTYGNSCANPFLYTLLTRNYRDHLRGRVRGPGSGGGRGPVPSLQPRARFQRCSGRSLSSCSPQPTDSLVLAPAAPARPAPEGPRAPA
  
Inhibitor
Name:
BDBM50302274
Synonyms:
(4R,10bR)-4-(3,4-dimethoxyphenyl)-10-(4-ethylpiperazin-1-yl)-1,2,3,4-tetrahydropyrido[2,1-a]isoindol-6(10bH)-one | CHEMBL566894
Type:
Small organic molecule
Emp. Form.:
C26H33N3O3
Mol. Mass.:
435.5585
SMILES:
CCN1CCN(CC1)c1cccc2C(=O)N3[C@H](CCC[C@@H]3c3ccc(OC)c(OC)c3)c12 |r|
Structure:
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