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Target
Procathepsin L
Ligand
BDBM50240948
Substrate
n/a
Meas. Tech.
ChEMBL_652318 (CHEMBL1225521)
Ki
9300±n/a nM
Citation
 Waag, T; Gelhaus, C; Rath, J; Stich, A; Leippe, M; Schirmeister, T Allicin and derivates are cysteine protease inhibitors with antiparasitic activity. Bioorg Med Chem Lett 20:5541-3 (2010) [PubMed]  Article 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM50240948
Synonyms:
CHEMBL359965 | S-allyl prop-2-ene-1-sulfinothioate | allicin | thio-2-propene-1-sulfinic acid S-allyl ester
Type:
Small organic molecule
Emp. Form.:
C6H10OS2
Mol. Mass.:
162.273
SMILES:
C=CCSS(=O)CC=C
Structure:
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