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Target
B1 bradykinin receptor
Ligand
BDBM50326708
Substrate
n/a
Meas. Tech.
ChEMBL_662799 (CHEMBL1252538)
Ki
6.5±n/a nM
Citation
 Huang, H; Player, MR Bradykinin B1 receptor antagonists as potential therapeutic agents for pain. J Med Chem 53:5383-99 (2010) [PubMed]  Article 
Target
Name:
B1 bradykinin receptor
Synonyms:
B1R | BK-1 receptor | BKRB1_MOUSE | Bdkrb | Bdkrb1
Type:
PROTEIN
Mol. Mass.:
37900.49
Organism:
Mus musculus
Description:
ChEMBL_662799
Residue:
334
Sequence:
MASQASLKLQPSNQSQQAPPNITSCEGAPEAWDLLCRVLPGFVITVCFFGLLGNLLVLSFFLLPWRRWWQQRRQRLTIAEIYLANLAASDLVFVLGLPFWAENVGNRFNWPFGSDLCRVVSGVIKANLFISIFLVVAISQDRYRLLVYPMTSWGNRRRRQAQVTCLLIWVAGGLLSTPTFLLRSVKVVPDLNISACILLFPHEAWHFVRMVELNVLGFLLPLAAILYFNFHILASLRGQKEASRTRCGGPKDSKTMGLILTLVASFLVCWAPYHFFAFLDFLVQVRVIQDCFWKELTDLGLQLANFFAFVNSCLNPLIYVFAGRLFKTRVLGTL
  
Inhibitor
Name:
BDBM50326708
Synonyms:
CHEMBL1254771 | N-(4-(4,5-dihydro-1H-imidazol-2-yl)benzyl)-2-(2-(4-methoxy-N,2,6-trimethylphenylsulfonamido)ethoxy)-N-methylacetamide
Type:
Small organic molecule
Emp. Form.:
C25H34N4O5S
Mol. Mass.:
502.626
SMILES:
COc1cc(C)c(c(C)c1)S(=O)(=O)N(C)CCOCC(=O)N(C)Cc1ccc(cc1)C1=NCCN1 |t:32|
Structure:
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