Reaction Details Report a problem with these data
Target
Transcriptional activator protein TraR
Ligand
BDBM50241433
Substrate
n/a
Meas. Tech.
ChEMBL_765233 (CHEMBL1827786)
IC50
920±n/a nM
Citation
 Lowery, CA; Salzameda, NT; Sawada, D; Kaufmann, GF; Janda, KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem 53:7467-89 (2010) [PubMed]  Article 
Target
Name:
Transcriptional activator protein TraR
Synonyms:
TRAR_RHIRD | traR
Type:
PROTEIN
Mol. Mass.:
26741.83
Organism:
Rhizobium radiobacter
Description:
ChEMBL_765233
Residue:
234
Sequence:
MQHWLDKLTDLAAIEGDECILKTGLADIADHFGFTGYAYLHIQHRHITAVTNYHRQWQSTYFDKKFEALDPVVKRARSRKHIFTWSGEHERPTLSKDERAFYDHASDFGIRSGITIPIKTANGFMSMFTMASDKPVIDLDREIDAVAAAATIGQIHARISFLRTTPTAEDAAWLDPKEATYLRWIAVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIRRKLI
  
Inhibitor
Name:
BDBM50241433
Synonyms:
(S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-yl)propanamide | (S)-3-(4-bromophenyl)-N-(2-oxotetrahydrofuran-3-yl)propanamide | CHEMBL264944
Type:
Small organic molecule
Emp. Form.:
C13H14BrNO3
Mol. Mass.:
312.159
SMILES:
Brc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r|
Structure:
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