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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50104411
Substrate
n/a
Meas. Tech.
ChEBML_33962
Ki
80000±n/a nM
Citation
 Dumas, DP; Kajimoto, T; Liu, KK; Wong, C; Berkowitz, DB; Danieshefsky, SJ Azasugar and glycal inhibitors of -L-fucosidase Bioorg Med Chem Lett 2:33-36 (1992)    Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50104411
Synonyms:
(R)-6-Methyl-tetrahydro-thiopyran-2,3,4,5-tetraol | CHEMBL313531
Type:
Small organic molecule
Emp. Form.:
C6H12O4S
Mol. Mass.:
180.222
SMILES:
CC1SC(O)C(O)[C@H](O)C1O
Structure:
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