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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50285244
Substrate
n/a
Meas. Tech.
ChEBML_216280
Ki
4900000±n/a nM
Citation
 Witczak, ZJ; Sun, J; Mielguj, R Synthesis of L-fucopyranosyl-4-thiodisaccharides from levoglucosenone and their inhibitory activity on -L-fucosidase Bioorg Med Chem Lett 5:2169-2174 (1995)    Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50285244
Synonyms:
CHEMBL303861 | Pent-4-enoic acid [(3S,5S)-2,4-dihydroxy-6-hydroxymethyl-5-((2S,4S,5S)-3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-ylsulfanyl)-tetrahydro-pyran-3-yl]-amide
Type:
Small organic molecule
Emp. Form.:
C17H29NO9S
Mol. Mass.:
423.478
SMILES:
CC1OC(SC2C(CO)OC(O)C(NC(=O)CCC=C)C2O)C(O)C(O)C1O
Structure:
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