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Target
alpha-1,2-Mannosidase
Ligand
BDBM50403869
Substrate
n/a
Meas. Tech.
ChEBML_32354
IC50
800000±n/a nM
Citation
 Popowycz, F; Gerber-Lemaire, S; Demange, R; Rodriguez-García, E; Asenjo, AT; Robina, I; Vogel, P Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors. Bioorg Med Chem Lett 11:2489-93 (2001) [PubMed]  Article 
Target
Name:
alpha-1,2-Mannosidase
Synonyms:
Alpha-mannosidase
Type:
PROTEIN
Mol. Mass.:
65344.50
Organism:
Glycine max
Description:
ChEMBL_32380
Residue:
578
Sequence:
MARGSRSVGSSSSKWRYCNPSYYLKRPKRLALLFIVFVCVSFVFWDRQTLVREHQVEISELQKEVTDLKNLVDDLNNKQGGTSGKTDLGRKATKSSKDVLDDPIDIERREKVKEAMLHAWGSYEKYAWGQDELQPQSKNGVNSFGGLGATLIDSLDTLYIMGLNEQFQKAREWVANSLDFNKDYEASVFETTIRVVGGLLSAYDLSGDKVFLDKAIEIADRLLPAWNTPTGIPYNIINLSHGRAHNPSWTGGESILADSGTEQLEFIVLSQRTGDLKYQQKVENVIAQLNKTFPDDGLLPIYINPHSGAAGYSPITFGAMGDSFYEYLLKVWIQGNKTSSIKHYRDMWEKSMKGLSSLIRRSTPSSFTYICEKNGGSLTDKMDELACFAPGMIALGSFGYSAADDSQKFLSLAEELAWTCYNFYQSTPTKLAGENYFFHSGQDMSVGTSWNILRPETVESLFYLWRLTGNKTYQEWGWNIFQAFEKNSRIESGYVGLKDVNSGVKDNMMQSFFLAETLKYFYLLFSPSSVISLDEWVFNTEAHPLRIVTRHEEGLVKNLNEKQKPFSRIGGRKEGRSG
  
Inhibitor
Name:
BDBM50403869
Synonyms:
CHEMBL2115197
Type:
Small organic molecule
Emp. Form.:
C6H13NO2
Mol. Mass.:
131.1729
SMILES:
CC[C@H]1NC[C@H](O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: