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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50009248
Substrate
n/a
Meas. Tech.
ChEMBL_159775 (CHEMBL763100)
IC50
2500±n/a nM
Citation
 Huff, JR HIV protease: a novel chemotherapeutic target for AIDS. J Med Chem 34:2305-14 (1991) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50009248
Synonyms:
(2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide | (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)oxirane-2-carboxamide | 3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide | 3-Nona-4,7-dienoyl-oxirane-2-carboxylic acid amide(Cerulenin) | CERULENIN | CHEMBL45627
Type:
Small organic molecule
Emp. Form.:
C12H17NO3
Mol. Mass.:
223.2683
SMILES:
C\C=C\C\C=C\CCC(=O)[C@H]1O[C@H]1C(N)=O |r|
Structure:
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