Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50001875
Substrate
n/a
Meas. Tech.
ChEBML_1808
Ki
95±n/a nM
Citation
 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR Pyrrole mannich bases as potential antipsychotic agents. J Med Chem 35:552-8 (1992) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B
Type:
Protein
Mol. Mass.:
43173.33
Organism:
Rattus norvegicus (Rat)
Description:
P28564
Residue:
386
Sequence:
MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
  
Inhibitor
Name:
BDBM50001875
Synonyms:
1-{5-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one | CHEMBL153451
Type:
Small organic molecule
Emp. Form.:
C22H29ClN4O
Mol. Mass.:
400.945
SMILES:
Cn1c(CN2CCN(CC2)c2cccc(Cl)c2)ccc1CN1CCCCC1=O
Structure:
Search PDB for entries with ligand similarity: