Reaction Details Report a problem with these data
Target
2-oxoglutarate receptor 1
Ligand
BDBM50369951
Substrate
n/a
Meas. Tech.
ChEMBL_151406 (CHEMBL754752)
Ki
833±n/a nM
Citation
 Umino, T; Yoshioka, K; Saitoh, Y; Minakawa, N; Nakata, H; Matsuda, A Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins. J Med Chem 44:208-14 (2001) [PubMed]  Article 
Target
Name:
2-oxoglutarate receptor 1
Synonyms:
G protein-coupled receptor 80 | Gpr80 | OXGR1_RAT | Oxgr1 | P2y15
Type:
PROTEIN
Mol. Mass.:
38385.93
Organism:
Rattus norvegicus
Description:
ChEMBL_151406
Residue:
337
Sequence:
MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVFKMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSSILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNRSACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKARRLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLLLYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP
  
Inhibitor
Name:
BDBM50369951
Synonyms:
CHEMBL609179
Type:
Small organic molecule
Emp. Form.:
C19H24N6O4
Mol. Mass.:
400.4317
SMILES:
Nc1ncnc2n(cnc12)C1O[C@@H]([C@@H](O)[C@H]1O)C(=O)NC12CC3CC(CC3C1)C2 |r,wU:12.19,wD:15.18,13.15,TLB:21:20:22.23:25,23:24:27:22.21,19:20:22.23:25,THB:21:22:25:20.27.28,23:22:27:24.25.28,(14.56,-1.07,;14.59,-2.62,;15.94,-3.39,;15.94,-4.93,;14.59,-5.72,;13.23,-4.95,;11.77,-5.42,;10.88,-4.16,;11.77,-2.92,;13.23,-3.39,;10.74,-6.56,;9.46,-5.74,;8.24,-6.72,;8.8,-8.16,;7.96,-9.46,;10.34,-8.06,;11.32,-9.25,;6.73,-6.37,;6.28,-4.88,;5.68,-7.47,;4.32,-7.5,;4.11,-8.82,;2.78,-9,;1.83,-9.94,;.64,-9.31,;.99,-8.02,;2.18,-7.81,;3.13,-6.88,;1.9,-6.86,)|
Structure:
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