Reaction Details Report a problem with these data
Target
2-oxoglutarate receptor 1
Ligand
BDBM50409303
Substrate
n/a
Meas. Tech.
ChEMBL_151406 (CHEMBL754752)
Ki
55.6±n/a nM
Citation
 Umino, T; Yoshioka, K; Saitoh, Y; Minakawa, N; Nakata, H; Matsuda, A Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins. J Med Chem 44:208-14 (2001) [PubMed]  Article 
Target
Name:
2-oxoglutarate receptor 1
Synonyms:
G protein-coupled receptor 80 | Gpr80 | OXGR1_RAT | Oxgr1 | P2y15
Type:
PROTEIN
Mol. Mass.:
38385.93
Organism:
Rattus norvegicus
Description:
ChEMBL_151406
Residue:
337
Sequence:
MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVFKMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSSILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNRSACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKARRLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLLLYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP
  
Inhibitor
Name:
BDBM50409303
Synonyms:
CHEMBL2092773
Type:
Small organic molecule
Emp. Form.:
C17H24N6O4
Mol. Mass.:
376.4103
SMILES:
C[C@H]1CC[C@H](CC1)NC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r,wU:12.18,10.10,4.7,1.0,wD:13.14,15.17,(-5.64,-3.71,;-4.16,-3.95,;-3.13,-2.74,;-1.62,-3.03,;-1.11,-4.47,;-2.11,-5.66,;-3.6,-5.37,;.43,-4.75,;1.43,-3.58,;.87,-2.12,;2.96,-3.86,;4.08,-2.81,;5.43,-3.58,;5.1,-5.07,;6.12,-6.22,;3.57,-5.21,;2.78,-6.54,;6.47,-2.43,;5.54,-1.19,;6.47,.07,;7.92,-.4,;9.27,.35,;9.27,1.88,;10.59,-.4,;10.59,-1.95,;9.27,-2.74,;7.92,-1.95,)|
Structure:
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