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Target
Carbonic anhydrase 4
Ligand
BDBM50108567
Substrate
n/a
Meas. Tech.
ChEMBL_45269 (CHEMBL658221)
Ki
6±n/a nM
Citation
 Masereel, B; Rolin, S; Abbate, F; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties. J Med Chem 45:312-20 (2002) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4
Type:
Enzyme
Mol. Mass.:
35152.74
Organism:
Bos taurus (bovine)
Description:
Bovine isozyme, isolated from lung microsomes
Residue:
312
Sequence:
MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAKTQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSRAMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQPLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQKPIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLAPVLACLTVGFLR
  
Inhibitor
Name:
BDBM50108567
Synonyms:
5-Phenylmethanesulfonylamino-[1,3,4]thiadiazole-2-sulfonic acid amide | Benzolamide, BZM | CHEMBL108982
Type:
Small organic molecule
Emp. Form.:
C9H10N4O4S3
Mol. Mass.:
334.395
SMILES:
NS(=O)(=O)c1nnc(NS(=O)(=O)Cc2ccccc2)s1
Structure:
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