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Target
Sortase family protein
Ligand
BDBM50372138
Substrate
n/a
Meas. Tech.
ChEMBL_464749 (CHEMBL930115)
IC50
181000±n/a nM
Citation
 Chenna, BC; Shinkre, BA; King, JR; Lucius, AL; Narayana, SV; Velu, SE Identification of novel inhibitors of bacterial surface enzyme Staphylococcus aureus Sortase A. Bioorg Med Chem Lett 18:380-5 (2008) [PubMed]  Article 
Target
Name:
Sortase family protein
Synonyms:
Sortase | Sortase A (SrtA)
Type:
Enzyme
Mol. Mass.:
23546.15
Organism:
Staphylococcus aureus
Description:
n/a
Residue:
206
Sequence:
MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
  
Inhibitor
Name:
BDBM50372138
Synonyms:
CHEMBL271487
Type:
Small organic molecule
Emp. Form.:
C18H18N2O5
Mol. Mass.:
342.3459
SMILES:
OC(=O)c1cc(NC(=O)\C=C\c2ccco2)ccc1N1CCOCC1
Structure:
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