Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50261053
Substrate
n/a
Meas. Tech.
ChEMBL_552264 (CHEMBL995594)
Ki
41±n/a nM
Citation
 Omura, H; Kawai, M; Shima, A; Iwata, Y; Ito, F; Masuda, T; Ohta, A; Makita, N; Omoto, K; Sugimoto, H; Kikuchi, A; Iwata, H; Ando, K The SAR studies of novel CB2 selective agonists, benzimidazolone derivatives. Bioorg Med Chem Lett 18:3310-4 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50261053
Synonyms:
1-(2-morpholinoethyl)-N-(naphthalen-1-yl)-2-oxo-1,2-dihydroquinazoline-3(4H)-carboxamide | CHEMBL494619
Type:
Small organic molecule
Emp. Form.:
C25H26N4O3
Mol. Mass.:
430.4989
SMILES:
O=C(Nc1cccc2ccccc12)N1Cc2ccccc2N(CCN2CCOCC2)C1=O
Structure:
Search PDB for entries with ligand similarity: