Reaction Details Report a problem with these data
Target
Transcriptional activator protein TraR
Ligand
BDBM50300133
Substrate
n/a
Meas. Tech.
ChEMBL_593847 (CHEMBL1049319)
IC50
1100±n/a nM
Citation
 Ahumedo, M; Díaz, A; Vivas-Reyes, R Theoretical and structural analysis of the active site of the transcriptional regulators LasR and TraR, using molecular docking methodology for identifying potential analogues of acyl homoserine lactones (AHLs) with anti-quorum sensing activity. Eur J Med Chem 45:608-15 (2010) [PubMed]  Article 
Target
Name:
Transcriptional activator protein TraR
Synonyms:
TRAR_RHIRD | traR
Type:
PROTEIN
Mol. Mass.:
26741.83
Organism:
Rhizobium radiobacter
Description:
ChEMBL_765233
Residue:
234
Sequence:
MQHWLDKLTDLAAIEGDECILKTGLADIADHFGFTGYAYLHIQHRHITAVTNYHRQWQSTYFDKKFEALDPVVKRARSRKHIFTWSGEHERPTLSKDERAFYDHASDFGIRSGITIPIKTANGFMSMFTMASDKPVIDLDREIDAVAAAATIGQIHARISFLRTTPTAEDAAWLDPKEATYLRWIAVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIRRKLI
  
Inhibitor
Name:
BDBM50300133
Synonyms:
CHEMBL573744 | N-(indole-3-butanoyl)-L-homoserine lactone
Type:
Small organic molecule
Emp. Form.:
C16H18N2O3
Mol. Mass.:
286.3257
SMILES:
O=C(CCCc1c[nH]c2ccccc12)N[C@H]1CCOC1=O |r|
Structure:
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