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Target
Solute carrier family 15 member 2
Ligand
BDBM50169199
Substrate
n/a
Meas. Tech.
ChEMBL_762551 (CHEMBL1817008)
Ki
39000±n/a nM
Citation
 Pedretti, A; De Luca, L; Marconi, C; Regazzoni, L; Aldini, G; Vistoli, G Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping. Bioorg Med Chem 19:4544-51 (2011) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 2
Synonyms:
Kidney H(+)/peptide cotransporter | Oligopeptide transporter, kidney isoform | PEPT2 | Peptide transporter 2 | S15A2_HUMAN | SLC15A2
Type:
PROTEIN
Mol. Mass.:
81795.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_762551
Residue:
729
Sequence:
MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSYYGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFDFVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLNLADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHSVQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVGEDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIEDIPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVLVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMIKLETKKTKL
  
Inhibitor
Name:
BDBM50169199
Synonyms:
(S)-2-(2-Amino-acetylamino)-3-(3H-imidazol-4-yl)-propionic acid | 2-(2-Amino-acetylamino)-3-(3H-imidazol-4-yl)-propionic acid | CHEMBL93127 | Gly-His
Type:
Small organic molecule
Emp. Form.:
C8H12N4O3
Mol. Mass.:
212.2059
SMILES:
NCC(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Structure:
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