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Targettrace amine-associated receptor 1
LigandBDBM50064817
Substrate/Competitorn/a
Meas. Tech.ChEMBL_882009
Ki 82±n/a nM
Citation Galley, GStalder, HGoergler, AHoener, MCNorcross, RD Optimisation of imidazole compounds as selective TAAR1 agonists: discovery of RO5073012. Bioorg Med Chem Lett22:5244-8 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
trace amine-associated receptor 1
Name:Trace amine-associated receptor 1
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:39107.47
Organism:Homo sapiens (Human)
Description:ChEMBL_792734
Residue:339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNW
LIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISID
RYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRG
GCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNG
ISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFN
PMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50064817
NameBDBM50064817
Synonyms:2-(2,6-Dimethyl-benzyl)-4,5-dihydro-1H-imidazole | CHEMBL71033
TypeSmall organic molecule
Emp. Form.C12H16N2
Mol. Mass.188.2688
SMILESCc1cccc(C)c1CC1=NCCN1 |t:10|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a