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Target
Peptide deformylase
Ligand
BDBM50411101
Substrate
n/a
Meas. Tech.
ChEMBL_400520 (CHEMBL912684)
IC50
7500±n/a nM
Citation
 Yoo, JS; Zheng, CJ; Lee, S; Kwak, JH; Kim, WG Macrolactin N, a new peptide deformylase inhibitor produced by Bacillus subtilis. Bioorg Med Chem Lett 16:4889-92 (2006) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
DEF_STAAM | PDF | Polypeptide deformylase | def | def1 | pdf1
Type:
Enzyme
Mol. Mass.:
20556.80
Organism:
Staphylococcus aureus
Description:
P68825
Residue:
183
Sequence:
MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKNHPLQPHTDAVEV
  
Inhibitor
Name:
BDBM50411101
Synonyms:
CHEMBL425430
Type:
Small organic molecule
Emp. Form.:
C24H34O4
Mol. Mass.:
386.5244
SMILES:
CC1CCC\C=C\CCC(=O)CCC\C=C/C=C/[C@@H](O)C\C=C\C=C/C(=O)O1 |c:14,23,t:5,16,21|
Structure:
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