Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 3
Ligand
BDBM50420215
Substrate
n/a
Meas. Tech.
ChEMBL_837470 (CHEMBL2075864)
Ki
15±n/a nM
Citation
 Gründemann, D; Schechinger, B; Rappold, GA; Schömig, E Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter. Nat Neurosci 1:349-51 (1999) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 3
Synonyms:
EMT | EMTH | Extraneuronal monoamine transporter | OCT3 | Organic cation transporter 3 | S22A3_HUMAN | SLC22A3
Type:
PROTEIN
Mol. Mass.:
61292.57
Organism:
Homo sapiens (Human)
Description:
ChEMBL_934315
Residue:
556
Sequence:
MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLGSPHSCKCGRNKKTPVSRSHL
  
Inhibitor
Name:
BDBM50420215
Synonyms:
CHEMBL339858
Type:
Small organic molecule
Emp. Form.:
C25H27N2
Mol. Mass.:
355.4947
SMILES:
CC(C)N1\C(=C/c2cc[n+](C(C)C)c3ccccc23)C=Cc2ccccc12 |c:21|
Structure:
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