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TargetNeutrophil collagenase
LigandBDBM50062462
Substrate/Competitorn/a
Meas. Tech.ChEMBL_458937
Ki 190546±n/a nM
Citation Verma, RPHansch, C Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs. Bioorg Med Chem15:2223-68 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neutrophil collagenase
Name:Neutrophil collagenase
Synonyms:MMP-8 | MMP8 | Matrix metalloproteinase-8 | Neutrophil collagenase precursor | PMNL collagenase | PMNL-CL
Type:Enzyme
Mol. Mass.:53413.48
Organism:Homo sapiens (Human)
Description:P22894
Residue:467
Sequence:
MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIV
EKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNY
TPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGIL
AHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYA
FRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKD
RYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQG
YPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGI
ESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG
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  Blast E-value cutoff:
BDBM50062462
NameBDBM50062462
Synonyms:2-Hydroxycarbamoyl-4-phenyl-butyric acid ethyl ester | CHEMBL116523 | ethyl 2-(hydroxycarbamoyl)-4-phenylbutanoate
TypeSmall organic molecule
Emp. Form.C13H17NO4
Mol. Mass.251.2784
SMILESCCOC(=O)C(CCc1ccccc1)C(=O)NO
Structure
n/a