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Target
Fibroblast growth factor 4
Ligand
BDBM50017347
Substrate
n/a
Meas. Tech.
ChEMBL_1363177 (CHEMBL3293892)
Kd
25000000±n/a nM
Citation
 Roy, S; El Hadri, A; Richard, S; Denis, F; Holte, K; Duffner, J; Yu, F; Galcheva-Gargova, Z; Capila, I; Schultes, B; Petitou, M; Kaundinya, GV Synthesis and biological evaluation of a unique heparin mimetic hexasaccharide for structure-activity relationship studies. J Med Chem 57:4511-20 (2014) [PubMed]  Article 
Target
Name:
Fibroblast growth factor 4
Synonyms:
FGF-4 | FGF4 | FGF4_HUMAN | HBGF-4 | HST | HST-1 | HSTF-1 | HSTF1 | Heparin secretory-transforming protein 1 | Heparin-binding growth factor 4 | KS3 | Transforming protein KS3
Type:
PROTEIN
Mol. Mass.:
22057.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108374
Residue:
206
Sequence:
MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPVAAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIALSKNGKTKKGNRVSPTMKVTHFLPRL
  
Inhibitor
Name:
BDBM50017347
Synonyms:
CHEMBL3288259
Type:
Small organic molecule
Emp. Form.:
C41H61N4Na9O49S6
Mol. Mass.:
1793.218
SMILES:
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H][C@]1(O[C@@H]2O[C@H]([C@@H](O)[C@H](O)[C@H]2OS([O-])(=O)=O)C([O-])=O)[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](O[C@@]2([H])[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@@]3([H])[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](O[C@@]4([H])[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@@]5([H])[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](OCCCCCN)O[C@@H]5CO)O[C@H]4C([O-])=O)O[C@@H]3CO)O[C@H]2C([O-])=O)O[C@@H]1CO |r|
Structure:
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