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Target
Adenosylhomocysteinase
Ligand
BDBM50105900
Substrate
n/a
Meas. Tech.
ChEMBL_1507790 (CHEMBL3598547)
Ki
1000±n/a nM
Citation
 Nakao, A; Suzuki, H; Ueno, H; Iwasaki, H; Setsuta, T; Kashima, A; Sunada, S Discovery and structural analyses of S-adenosyl-L-homocysteine hydrolase inhibitors based on non-adenosine analogs. Bioorg Med Chem 23:4952-69 (2015) [PubMed]  Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
Adenosylhomocysteinase | Ahcy | SAHH_RAT
Type:
PROTEIN
Mol. Mass.:
47537.52
Organism:
Rattus norvegicus
Description:
ChEMBL_1507790
Residue:
432
Sequence:
MADKLPYKVADIGLAAWGRKALDIAENEMPGLMRMREMYSASKPLKGARIAGCLHMTVETAVLIETLVALGAEVRWSSCNIFSTQDHAAAAIAKAGIPVFAWKGETDEEYLWCIEQTLHFKDGPLNMILDDGGDLTNLIHTKHPQLLSGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACKEGNIFVTTTGCVDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYLLKNGHRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMPINGPFKPDHYRY
  
Inhibitor
Name:
BDBM50105900
Synonyms:
CHEMBL11390
Type:
Small organic molecule
Emp. Form.:
C8H11N5O2
Mol. Mass.:
209.2052
SMILES:
Nc1ncnc2n(CC(O)CO)cnc12
Structure:
Search PDB for entries with ligand similarity: