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TargetAdenosine receptor A3
LigandBDBM50116882
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1515687
Ki 5.8±n/a nM
Citation Tosh, DKCrane, SChen, ZPaoletta, SGao, ZGGizewski, EAuchampach, JASalvemini, DJacobson, KA Rigidified A3 Adenosine Receptor Agonists: 1-Deazaadenine Modification Maintains High in Vivo Efficacy. ACS Med Chem Lett6:804-8 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A3
Name:Adenosine receptor A3
Synonyms:ADORA3 | Adenosine receptor A3
Type:PROTEIN
Mol. Mass.:35914.81
Organism:Canis lupus familiaris
Description:ChEMBL_109866
Residue:314
Sequence:
MAVNGTALLLANVTYITVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVISLGITIQFYNCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYRR
VTTQRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEHQRNVTFLSCQFSSVMRMDYMVYF
SFFTWILIPLVVMCAIYLDIFYVIRNKLNQNFSSSKETGAFYGREFKTAKSLFLVLFLFA
FSWLPLSIINCITYFHGEVPQIILYLGILLSHANSMMNPIVYAYKIKKFKETYLLIFKTY
MICQSSDSLDSSTE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50116882
NameBDBM50116882
Synonyms:CHEMBL3612932
TypeSmall organic molecule
Emp. Form.C22H23ClN6O3S
Mol. Mass.486.974
SMILES[H][C@]12C[C@]1([C@@H](O)[C@@H](O)[C@@H]2n1cnc2c(NCCC)nc(nc12)C#Cc1ccc(Cl)s1)C(=O)NC |r|
Structure
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