Reaction Details Report a problem with these data
Target
D(4) dopamine receptor
Ligand
BDBM50213967
Substrate
n/a
Meas. Tech.
ChEMBL_61327 (CHEMBL670102)
Ki
20±n/a nM
Citation
  TBA Bioorg Med Chem Lett 6:1227-1232 (1996)   
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50213967
Synonyms:
CHEMBL21119
Type:
Small organic molecule
Emp. Form.:
C25H36ClN3O
Mol. Mass.:
430.026
SMILES:
Clc1ccc(cc1)N1CCN(CCCCNC(=O)C23CC4CC(CC(C4)C2)C3)CC1 |TLB:21:22:26:19.20.25,THB:23:22:19:26.24.25,23:24:19:27.22.21,21:20:26:27.22.23|
Structure:
Search PDB for entries with ligand similarity: