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Target
Phosphatidylinositol 4-kinase type 2-alpha
Ligand
BDBM50368125
Substrate
n/a
Meas. Tech.
ChEMBL_152907 (CHEMBL758630)
Ki
100100±n/a nM
Citation
 Young, RC; Jones, M; Milliner, KJ; Rana, KK; Ward, JG Purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase. J Med Chem 33:2073-80 (1990) [PubMed]  Article 
Target
Name:
Phosphatidylinositol 4-kinase type 2-alpha
Synonyms:
P4K2A_HUMAN | PI4K2A | Phosphatidylinositol 4-kinase type 2-alpha | Phosphatidylinositol 4-kinase type II-alpha
Type:
PROTEIN
Mol. Mass.:
54030.26
Organism:
Homo sapiens (Human)
Description:
ChEMBL_104812
Residue:
479
Sequence:
MDETSPLVSPERAQPPDYTFPSGSGAHFPQVPGGAVRVAAAAGSGPSPPGSPGHDRERQPLLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRERNEFPEDPEFEAVVRQAELAIERCIFPERIYQGSSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDSSSSRDTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSHQRSSSESYTQSFQSRKPFFSWW
  
Inhibitor
Name:
BDBM50368125
Synonyms:
ADENOSINE DIPHOSPHATE | ADP
Type:
Small organic molecule
Emp. Form.:
C10H15N5O10P2
Mol. Mass.:
427.2011
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure:
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