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Target
Serine protease 1
Ligand
BDBM50230149
Substrate
n/a
Meas. Tech.
ChEBML_212371
KOFF
0.000333 s-1
Citation
 Rai, R; Katzenellenbogen, JA Guanidinophenyl-substituted enol lactones as selective, mechanism-based inhibitors of trypsin-like serine proteases. J Med Chem 35:4150-9 (1992) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50230149
Synonyms:
CHEMBL1161040
Type:
Small organic molecule
Emp. Form.:
C13H14IN3O2
Mol. Mass.:
371.1736
SMILES:
NC(=N)Nc1ccc(cc1)C1CC(=O)O\C(C1)=C\I
Structure:
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