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Target
D(3) dopamine receptor
Ligand
BDBM50041959
Substrate
n/a
Ki
437.7±n/a nM
Comments
PDSP_260
Citation
 Boundy, VA; Luedtke, RR; Gallitano, AL; Smith, JE; Filtz, TM; Kallen, RG; Molinoff, PB Expression and characterization of the rat D3 dopamine receptor: pharmacologic properties and development of antibodies. J Pharmacol Exp Ther 264:1002-11 (1993) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3
Type:
Protein
Mol. Mass.:
49540.58
Organism:
Rattus norvegicus (Rat)
Description:
P19020
Residue:
446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50041959
Synonyms:
((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine | (+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine | (1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine | (5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine | AJ76(+) | CHEMBL27441
Type:
Small organic molecule
Emp. Form.:
C15H23NO
Mol. Mass.:
233.3492
SMILES:
CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C
Structure:
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