Reaction Details Report a problem with these data
Target
Nicotinic acetylcholine receptor
Ligand
BDBM81888
Substrate
n/a
Ki
3789±n/a nM
Comments
PDSP_593
Citation
 Dávila-García, MI; Musachio, JL; Perry, DC; Xiao, Y; Horti, A; London, ED; Dannals, RF; Kellar, KJ [125I]IPH, an epibatidine analog, binds with high affinity to neuronal nicotinic cholinergic receptors. J Pharmacol Exp Ther 282:445-51 (1997) [PubMed] 
Target
Name:
Nicotinic acetylcholine receptor
Synonyms:
Nicotinic acetylcholine receptor | n-AChR
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2478.99
Organism:
RAT
Description:
n-AChR 0 RAT::Q62594
Residue:
23
Sequence:
MTMALLGTLLLLALFGRSQGKNE
  
Inhibitor
Name:
BDBM81888
Synonyms:
CAS_8063-06-7 | Curare | NSC_411885
Type:
Small organic molecule
Emp. Form.:
C38H44N2O6
Mol. Mass.:
624.7647
SMILES:
COc1cc2CC[N+](C)(C)C3Cc4ccc(O)c(Oc5cc6C(Cc7ccc(Oc(c1O)c23)cc7)[N+](C)(C)CCc6cc5OC)c4
Structure:
Search PDB for entries with ligand similarity: