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Target
Kappa-type opioid receptor
Ligand
BDBM86518
Substrate
n/a
Ki
33.6±n/a nM
Comments
PDSP_669
Citation
 Gilbert, AK; Hosztafi, S; Mahurter, L; Pasternak, GW Pharmacological characterization of dihydromorphine, 6-acetyldihydromorphine and dihydroheroin analgesia and their differentiation from morphine. Eur J Pharmacol 492:123-30 (2004) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | OPIATE Kappa | OPIATE Kappa 3 | OPRK1 | OPRK_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42629.84
Organism:
CALF
Description:
Q2KIP6
Residue:
380
Sequence:
MEPPVQIFRGEPGPTCSPSTCLPPNGSGWFPGWAEPDGNGSAGSEDVLLEPAHISPVILVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKVVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWILSSSVGISAIVLGGTKVREDMEVIECSLQFPDDDYSWWDLFMKVCVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTAHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYVREVDGVNKPV
  
Inhibitor
Name:
BDBM86518
Synonyms:
CAS_509-60-4 | DIHYDROMORPHINE | NSC_273032
Type:
Small organic molecule
Emp. Form.:
C17H21NO3
Mol. Mass.:
287.3535
SMILES:
CN1CCC23C4Oc5c2c(CC1C3CCC4O)ccc5O |TLB:13:12:1.2.3:10.9.8|
Structure:
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