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Target
Melanocortin receptor 4
Ligand
BDBM88522
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89220±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88522
Synonyms:
4-[1-amino-2-(4-chlorophenyl)ethyl]-N-(4,6-dimethyl-2-pyrimidinyl)-2-thiazolamine | 4-[1-amino-2-(4-chlorophenyl)ethyl]-N-(4,6-dimethylpyrimidin-2-yl)-1,3-thiazol-2-amine | 4-[1-azanyl-2-(4-chlorophenyl)ethyl]-N-(4,6-dimethylpyrimidin-2-yl)-1,3-thiazol-2-amine | MLS003123700 | SMR001291736 | [4-[1-amino-2-(4-chlorophenyl)ethyl]thiazol-2-yl]-(4,6-dimethylpyrimidin-2-yl)amine | cid_46948249
Type:
Small organic molecule
Emp. Form.:
C17H18ClN5S
Mol. Mass.:
359.876
SMILES:
Cc1cc(C)nc(Nc2nc(cs2)C(N)Cc2ccc(Cl)cc2)n1
Structure:
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