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Target
ADP-ribosylation factor GTPase-activating protein 1
Ligand
BDBM94668
Substrate
n/a
IC50
36559±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) PubChem Bioassay (2012)[AID] 
Target
Name:
ADP-ribosylation factor GTPase-activating protein 1
Synonyms:
ARFG1_RAT | Arf1gap | Arfgap1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45436.38
Organism:
Rattus norvegicus
Description:
gi_21489979
Residue:
415
Sequence:
MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQENRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEDTSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSSDSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW
  
Inhibitor
Name:
BDBM94668
Synonyms:
4-acetamido-N-(4-pyridin-3-yl-1,3-thiazol-2-yl)benzamide | 4-acetamido-N-[4-(3-pyridinyl)-2-thiazolyl]benzamide | 4-acetamido-N-[4-(3-pyridyl)thiazol-2-yl]benzamide | MLS001010721 | SMR000385055 | cid_2463732
Type:
Small organic molecule
Emp. Form.:
C17H14N4O2S
Mol. Mass.:
338.384
SMILES:
CC(=O)Nc1ccc(cc1)C(=O)Nc1nc(cs1)-c1cccnc1
Structure:
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