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Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM68155
Substrate
n/a
IC50
12218±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM68155
Synonyms:
MLS001005764 | SMR000384079 | cid_16196355 | nitric acid;2-[(1-phenyl-3-thiophen-2-yl-4-pyrazolyl)methylideneamino]guanidine | nitric acid;2-[(1-phenyl-3-thiophen-2-yl-pyrazol-4-yl)methylideneamino]guanidine | nitric acid;2-[(1-phenyl-3-thiophen-2-ylpyrazol-4-yl)methylideneamino]guanidine | nitric acid;2-[(E)-[1-phenyl-3-(2-thienyl)pyrazol-4-yl]methyleneamino]guanidine | nitric acid;2-[[1-phenyl-3-(2-thienyl)pyrazol-4-yl]methyleneamino]guanidine
Type:
Small organic molecule
Emp. Form.:
C15H14N6S
Mol. Mass.:
310.377
SMILES:
[#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1cn(nc1-c1cccs1)-c1ccccc1 |w:4.3|
Structure:
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