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Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96787
Substrate
n/a
IC50
18342±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G protein alpha 16 | G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | Guanine nucleotide-binding protein subunit alpha-15 [Y147C]
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96787
Synonyms:
2-[[2-(2-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfonyl]-N-(2-phenylethyl)acetamide | 2-[[2-(2-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfonyl]-N-(2-phenylethyl)ethanamide | 2-[[2-(2-chlorophenyl)-5-methyl-4-oxazolyl]methylsulfonyl]-N-(2-phenylethyl)acetamide | 2-[[2-(2-chlorophenyl)-5-methyl-oxazol-4-yl]methylsulfonyl]-N-phenethyl-acetamide | MLS000925119 | SMR000624101 | cid_20876730
Type:
Small organic molecule
Emp. Form.:
C21H21ClN2O4S
Mol. Mass.:
432.92
SMILES:
Cc1oc(nc1CS(=O)(=O)CC(=O)NCCc1ccccc1)-c1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: