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Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96807
Substrate
n/a
IC50
>29870±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | guanine nucleotide-binding protein subunit alpha-15
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96807
Synonyms:
1-[2,5-dimethyl-1-(2-phenylethyl)-3-pyrrolyl]-2-[4-(1,1-dioxo-3-thiolanyl)-1-piperazinyl]ethanone | 1-[2,5-dimethyl-1-(2-phenylethyl)pyrrol-3-yl]-2-[4-(1,1-dioxothiolan-3-yl)piperazin-1-yl]ethanone | 2-[4-(1,1-diketothiolan-3-yl)piperazino]-1-(2,5-dimethyl-1-phenethyl-pyrrol-3-yl)ethanone | 2-[4-[1,1-bis(oxidanylidene)thiolan-3-yl]piperazin-1-yl]-1-[2,5-dimethyl-1-(2-phenylethyl)pyrrol-3-yl]ethanone | MLS002170213 | SMR001250534 | cid_16330350
Type:
Small organic molecule
Emp. Form.:
C24H33N3O3S
Mol. Mass.:
443.602
SMILES:
Cc1cc(C(=O)CN2CCN(CC2)C2CCS(=O)(=O)C2)c(C)n1CCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: