Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM100219
Substrate
n/a
IC50
4408±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM100219
Synonyms:
MLS000733369 | N-cyclooctyl-5-(6-quinolinyloxymethyl)-3-isoxazolecarboxamide | N-cyclooctyl-5-(6-quinolyloxymethyl)isoxazole-3-carboxamide | N-cyclooctyl-5-(quinolin-6-yloxymethyl)-1,2-oxazole-3-carboxamide | N-cyclooctyl-5-[(quinolin-6-yloxy)methyl]isoxazole-3-carboxamide | SMR000315956 | cid_16189691
Type:
Small organic molecule
Emp. Form.:
C22H25N3O3
Mol. Mass.:
379.4522
SMILES:
O=C(NC1CCCCCCC1)c1cc(COc2ccc3ncccc3c2)on1
Structure:
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