Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM130387
Substrate
n/a
Meas. Tech.
Binding Assay
pH
7.5±n/a
Temperature
298.15±n/a K
IC50
0.47±n/a nM
Comments
extracted
Citation
 Das, J; Koo, SS; Srivastava, AS; Moquin, RV; Watterson, SH Substituted 3-phenyl-1,2,4-Oxadiazole compounds US Patent  US8822510 Publication Date 9/2/2014 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM130387
Synonyms:
US8822510, 9
Type:
Small organic molecule
Emp. Form.:
C28H32FN3O3
Mol. Mass.:
477.5704
SMILES:
OC(=O)C1CN(Cc2ccc(cc2)-c2noc(CCCC3(CCCCC3)c3ccc(F)cc3)n2)C1
Structure:
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