Reaction Details Report a problem with these data
Target
NADH-ubiquinone oxidoreductase chain 1
Ligand
BDBM144634
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.4±n/a
IC50
10700±n/a nM
Comments
extracted
Citation
 Hecht, S; Khdour, O; Lu, J; Arce, P Multifunctional radical quenchers and their uses US Patent  US8952025 Publication Date 2/10/2015 
Target
Name:
NADH-ubiquinone oxidoreductase chain 1
Synonyms:
MT-ND1 | MTND1 | NADH Oxidase | NADH-ubiquinone oxidoreductase | NADH-ubiquinone oxidoreductase chain 1 | NADH1 | ND1 | NU1M_BOVIN
Type:
Protein
Mol. Mass.:
35672.63
Organism:
Bos taurus (Bovine)
Description:
P03887
Residue:
318
Sequence:
MFMINILMLIIPILLAVAFLTLVERKVLGYMQLRKGPNVVGPYGLLQPIADAIKLFIKEPLRPATSSASMFILAPIMALGLALTMWIPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMSGSFTLSTLITTQEQMWLILPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYANIIMMNIFTAILFLGTSHNPHMPELYTINFTIKSLLLTMSFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVSLPILTSGIPPQT
  
Inhibitor
Name:
BDBM144634
Synonyms:
US8952025, Compound 4, table 3
Type:
Small organic molecule
Emp. Form.:
C21H37N3O
Mol. Mass.:
347.538
SMILES:
CCCCCCCCCCc1nc(nc(C)c1O)N1C(C)CCC1C
Structure:
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