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TargetCyclin-dependent kinase 2
LigandBDBM164884
Substrate/Competitorn/a
Meas. Tech. In Vitro Kinase Inhibition Assay
pH7.5±n/a
IC50 913±n/a nM
Commentsextracted
Citation Zeitlmann, LNiestroj, AHeiser, U Inhibitors of protein kinases US Patent US9067888 Publication Date 6/30/2015
More Info.:Get all data from this article,  Assay Method
 
Cyclin-dependent kinase 2
Name:Cyclin-dependent kinase 2
Synonyms:CDK2 | CDK2-Kinase | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | p33 protein kinase
Type:Enzyme Subunit
Mol. Mass.:33938.17
Organism:Homo sapiens (Human)
Description:P24941
Residue:298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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BDBM164884
NameBDBM164884
Synonyms:US9067888, 34
TypeSmall organic molecule
Emp. Form.C20H22FN3O3
Mol. Mass.371.4054
SMILESCOc1cc(F)ccc1-c1ccnc(NC(=O)C2CCC(C2)NC(C)=O)c1
Structure
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